Depopulate

v. t.	1.	To deprive of inhabitants, whether by death or by expulsion; to reduce greatly the populousness of; to dispeople; to unpeople. [imp. & p. p. Depopulated ; p. pr. & vb. n. Depopulating .] Where is this viper, That would depopulate the city? - Shak.
v. i.	1.	To become dispeopled. Whether the country be depopulating or not. - Goldsmith.

Verb

1.

depopulate - reduce in population; "The epidemic depopulated the countryside" Synonyms: desolate

depopulation, desolate, reduce, shrink