Setback

n.	1.	(Arch.) Offset, n., 4.
	2.	A backset; a countercurrent; an eddy.
	3.	A reversal of progress in an endeavor; a reverse; a backset; a check; a repulse; a relapse.

Noun

1.

setback - an unfortunate happening that hinders of impedes; something that is thwarting or frustrating Synonyms: reversal, reverse, black eye, blow

arrest, arrestation, arrestment, atavism, backset, backsliding, backward deviation, backward motion, backward step, bafflement, balk, betrayed hope, blasted expectation, blighted hope, blockage, blocking, blow, buffet, check, checkmate, clogging, closing up, closure, comedown, confusion, constriction, cramp, cruel disappointment, dash, dashed hope, deceleration, defeat, delay, descent, detainment, detention, disappointment, discomfiture, disillusionment, dissatisfaction, down, drag, ease-off, ease-up, failure, fallen countenance, falling back, fiasco, fixation, fizzle, flagging, foil, foiling, foot-dragging, forlorn hope, frustration, hampering, hindering, hindrance, holdback, holdup, hope deferred, impediment, inhibition, interference, interruption, lag, lapse, let, letdown, letup, minus acceleration, mirage, negativism, nuisance value, obstacle, obstruction, obstructionism, occlusion, opposition, reaction, rebuff, recession, recidivation, recidivism, recrudescence, recurrence, reentry, refluence, reflux, regress, regression, relapse, renewal, repression, repulse, resistance, restraint, restriction, retardation, retardment, retroaction, retrocession, retroflexion, retrogradation, retrogression, retrusion, return, reversal, reverse, reverse of fortune, reversion, rollback, rout, severe check, slack-up, slackening, slowdown, slowing, slowing down, slowup, sore disappointment, squeeze, sternway, stranglehold, stricture, stumbling block, suppression, tantalization, tease, throwback