Irreversible

a.	1.	Incapable of being reversed or turned about or back; incapable of being made to run backward; as, an irreversible engine; an irreversible process; an irreversible reaction.
	2.	Incapable of being reversed, recalled, repealed, or annulled; as, an irreversible sentence or decree. This rejection of the Jews, as it is not universal, so neither is it final and irreversible. - Jortin.

Adj.	1.	irreversible - impossible to reverse or be reversed; "irreversible momentum toward revolution" Antonyms: reversible - capable of reversing or being reversed; "reversible hypertension"
	2.	irreversible - impossible to reverse or undo; "an irreversible decree"

beyond recall, beyond remedy, changeless, chronic, confirmed, constant, cureless, deep-dyed, deep-fixed, deep-rooted, deep-seated, deep-set, deep-settled, direct, dyed-in-the-wool, established, fast, final, fixed, gone, immediate, immedicable, immutable, implanted, incommutable, inconvertible, incorrigible, inculcated, incurable, indefeasible, inert, infixed, ingrained, inoperable, instilled, insusceptible of change, intransmutable, invariable, inveterate, irreclaimable, irrecoverable, irredeemable, irreformable, irremediable, irreparable, irretrievable, irrevocable, lasting, long-established, lost, noble, nonreturnable, nonreversible, one-way, past hope, past praying for, permanent, remediless, reverseless, rooted, ruined, set, settled, settled in habit, straight, straightaway, straightforward, straightway, terminal, thorough, unalterable, unalterative, unaltered, unbroken, unchangeable, unchanged, unchanging, undeflectable, undeviating, undone, unidirectional, uninterrupted, unmitigable, unmodifiable, unrelievable, unremitting, unrestorable, unreturnable, unsalvable, unsalvageable, unsusceptible, unswerving, unvariable, unvarying